People Publications
Margaret Fang, MD
Assessment of algorithms to identify patients with thrombophilia following venous thromboembolism. Thrombosis research 2015.
Delate T, Hsiao W, Kim B, Witt DM, Meyer MR, Go AS, Fang MC.
Development of a Novel Bleeding Quality of Life Patient-Reported Outcome Measure for Older Adults. Blood 2022.
Anna L Parks, Alyssa Lopez, Stacey L. Slager, Margaret C. Fang, Mark A. Supiano, Patti P Katz, Daniel M. Witt.
Comparison of frequency and outcome of major gastrointestinal hemorrhage in patients with atrial fibrillation on versus not receiving warfarin therapy (from the ATRIA and ATRIA-CVRN cohorts). The American journal of cardiology 2014.
Ashburner JM, Go AS, Reynolds K, Chang Y, Fang MC, Fredman L, Applebaum KM, Singer DE.
Comparison of risk stratification schemes to predict thromboembolism in people with nonvalvular atrial fibrillation. Journal of the American College of Cardiology 2008.
Fang MC, Go AS, Chang Y, Borowsky L, Pomernacki NK, Singer DE.
Assessment of the Risk of Venous Thromboembolism in Nonhospitalized Patients With COVID-19. JAMA network open 2023.
Fang MC, Reynolds K, Tabada GH, Prasad PA, Sung SH, Parks AL, Garcia E, Portugal C, Fan D, Pai AP, Go AS.
Warfarin or Not Warfarin?. Annals of internal medicine 2005.
Margaret C. Fang, Daniel E. Singer.
Apixaban Concentrations in Routine Clinical Care of Older Adults With Nonvalvular Atrial Fibrillation. JACC Advances 2022.
Alveena Thomas, Margaret C. Fang, Scott Kogan, Colin C. Hubbard, Paula N. Friedman, Li Gong, Teri E. Klein, Edith A. Nutescu, Travis J. O'Brien, Matthew Tuck, Minoli A. Perera, Janice B. Schwartz.
Thrombophilia testing patterns amongst patients with acute venous thromboembolism. Thrombosis research 2015.
Meyer MR, Witt DM, Delate T, Johnson SG, Fang M, Go A, Clark NP.
Get With The Guidelines AFIB: novel quality improvement registry for hospitalized patients with atrial fibrillation. Circulation. Cardiovascular quality and outcomes 2014.
Lewis WR, Piccini JP, Turakhia MP, Curtis AB, Fang M, Suter RE, Page RL, Fonarow GC.
Atrial fibrillation in the elderly. The American journal of medicine 2007.
Fang MC, Chen J, Rich MW.
Racial and Ethnic Disparities in Discharge Opioid Prescribing From a Hospital Medicine Service. Journal of hospital medicine 2021.
Rambachan A, Fang MC, Prasad P, Iverson N.
Outcomes in adults with acute pulmonary embolism who are discharged from emergency departments: the Cardiovascular Research Network Venous Thromboembolism study. JAMA internal medicine 2015.
Fang MC, Fan D, Sung SH, Witt DM, Yale SH, Steinhubl SR, Go AS.
Contemporary use of dual antiplatelet therapy for preventing cardiovascular events. The American journal of managed care 2014.
Goldsweig AM, Reid KJ, Gosch K, Tang F, Fang MC, Maddox TM, Chan PS, Cohen DJ, Chen J.
Death and disability from warfarin-associated intracranial and extracranial hemorrhages. The American journal of medicine 2007.
Fang MC, Go AS, Chang Y, Hylek EM, Henault LE, Jensvold NG, Singer DE.
Long-term functional outcomes and mortality after hospitalization for extracranial hemorrhage. 2015 Year Book of Pediatrics. Ed. Cabana MD. (Elsevier; Philadelphia, PA) 2022.
Parks AL, Jeon SY, Boscardin WJ, Steinman MA, Smith AK, Covinsky KE, Fang MC, Shah SJ.
Implications of the new atrial fibrillation guideline. JAMA internal medicine 2015.
Fang MC.
Effect of selective serotonin reuptake inhibitors on bleeding risk in patients with atrial fibrillation taking warfarin. The American journal of cardiology 2014.
Quinn GR, Singer DE, Chang Y, Go AS, Borowsky LH, Udaltsova N, Fang MC.
Preparing for "diastole": advanced training opportunities for academic hospitalists. Journal of hospital medicine 2006.
Arora V, Fang MC, Kripalani S, Amin AN.
Sex and Race/Ethnicity Differences in Atrial Fibrillation. Journal of the American College of Cardiology 2019.
Volgman AS, Bairey Merz CN, Benjamin EJ, Curtis AB, Fang MC, Lindley KJ, Pepine CJ, Vaseghi M, Waldo AL, Wenger NK, Russo AM.
Sex Disparities in Opioid Prescription and Administration on a Hospital Medicine Service. Journal of general internal medicine 2024.
Yang N, Fang MC, Rambachan A.
Predictive value of the present-on-admission indicator for hospital-associated hemorrhage. Thrombosis research 2019.
Ghazvinian R, White RH, Gage BF, Fang MC, Saeed R, Khanna RR.
Internal medicine rounding practices and the Accreditation Council for Graduate Medical Education core competencies. Journal of hospital medicine 2014.
Shoeb M, Khanna R, Fang M, Sharpe B, Finn K, Ranji S, Monash B.
Guidelines for the prevention of stroke in patients with stroke and transient ischemic attack: a guideline for healthcare professionals from the American Heart Association/American Stroke Association. Stroke 2014.
Kernan WN, Ovbiagele B, Black HR, Bravata DM, Chimowitz MI, Ezekowitz MD, Fang MC, Fisher M, Furie KL, Heck DV, Johnston SC, Kasner SE, Kittner SJ, Mitchell PH, Rich MW, Richardson D, Schwamm LH, Wilson JA.
Age and the risk of warfarin-associated hemorrhage: the anticoagulation and risk factors in atrial fibrillation study. Journal of the American Geriatrics Society 2006.
Fang MC, Go AS, Hylek EM, Chang Y, Henault LE, Jensvold NG, Singer DE.
Bridging Anticoagulation Therapy: A Teachable Moment. JAMA internal medicine 2019.
Kulkarni SA, Fang MC.
Pain Assessment Disparities by Race, Ethnicity, and Language in Adult Hospitalized Patients. Pain management nursing : official journal of the American Society of Pain Management Nurses 2023.
Rambachan A, Noorulhuda H, Fang MC, Bazinski M, Manuel S, Hubbard C, Prasad P.
Trends in stroke rates, risk, and outcomes in the United States, 1988 to 2008. The American journal of medicine 2014.
Fang MC, Coca Perraillon M, Ghosh K, Cutler DM, Rosen AB.
Health literacy and anticoagulation-related outcomes among patients taking warfarin. Journal of general internal medicine 2006.
Fang MC, Machtinger EL, Wang F, Schillinger D.
Transitions in Care: Inpatient Anticoagulation. Inpatient Anticoagulation 2011.
Neil Gupta, Diane Sliwka, Margaret C. Fang.
Long-term survival after ischemic stroke in patients with atrial fibrillation. Neurology 2014.
Fang MC, Go AS, Chang Y, Borowsky LH, Pomernacki NK, Udaltsova N, Singer DE.
Gender differences in the risk of ischemic stroke and peripheral embolism in atrial fibrillation: the AnTicoagulation and Risk factors In Atrial fibrillation (ATRIA) study. Circulation 2005.
Fang MC, Singer DE, Chang Y, Hylek EM, Henault LE, Jensvold NG, Go AS.
Chapter 15 Anticoagulant and Antiplatelet Drug Therapy in Atrial Fibrillation. Clinical Trials in Heart Disease 2004.
Daniel E. Singer, Elaine M. Hylek, Margaret C. Fang.
Assessing for differences in opioid administration during inpatient end-of-life care for patients with limited English proficiency. Journal of hospital medicine 2024.
Curatola N, Prasad P, Bell BK, Fang MC, Rambachan A.
Social Determinants of Health, Income, and Anticoagulation Outcomes. Journal of the American College of Cardiology 2022.
Fang MC.
A pharmacogenetic versus a clinical algorithm for warfarin dosing. The New England journal of medicine 2013.
Kimmel SE, French B, Kasner SE, Johnson JA, Anderson JL, Gage BF, Rosenberg YD, Eby CS, Madigan RA, McBane RB, Abdel-Rahman SZ, Stevens SM, Yale S, Mohler ER, Fang MC, Shah V, Horenstein RB, Limdi NA, Muldowney JA, Gujral J, Delafontaine P, Desnick RJ, Ortel TL, Billett HH, Pendleton RC, Geller NL, Halperin JL, Goldhaber SZ, Caldwell MD, Califf RM, Ellenberg JH.
Antithrombotic therapy for stroke prevention in atrial fibrillation. Progress in cardiovascular diseases 2005.
Go AS, Fang MC, Singer DE.
The Association between Limited English Proficiency and Sepsis Mortality. Journal of hospital medicine 2019.
Jacobs ZG, Prasad PA, Fang MC, Abe-Jones Y, Kangelaris KN.
Associations of Physician Empathy with Patient Anxiety and Ratings of Communication in Hospital Admission Encounters. Journal of hospital medicine 2017.
Weiss R, Vittinghoff E, Fang MC, Cimino JEW, Chasteen KA, Arnold RM, Auerbach AD, Anderson WG.
Prevalence and Knowledge of Potential Interactions Between Over-the-Counter Products and Apixaban. Journal of the American Geriatrics Society 2019.
Tarn DM, Barrientos M, Wang AY, Ramaprasad A, Fang MC, Schwartz JB.
A new risk scheme to predict ischemic stroke and other thromboembolism in atrial fibrillation: the ATRIA study stroke risk score. Journal of the American Heart Association 2013.
Singer DE, Chang Y, Borowsky LH, Fang MC, Pomernacki NK, Udaltsova N, Reynolds K, Go AS.
Cost considerations surrounding current and future anticoagulant therapies. Cleveland Clinic journal of medicine 2005.
Fang MC, Minichiello T, Auerbach AD.
Estimating Vitamin K Antagonist Anticoagulation Benefit in People With Atrial Fibrillation Accounting for Competing Risks: Evidence From 12 Randomized Trials. Circulation. Cardiovascular quality and outcomes 2024.
Shah SJ, van Walraven C, Jeon SY, Boscardin J, Hobbs FDR, Connolly SJ, Ezekowitz MD, Covinsky KE, Fang MC, Singer DE.
Treatment and Outcomes of Acute Pulmonary Embolism and Deep Venous Thrombosis: The CVRN VTE Study. The American journal of medicine 2019.
Fang MC, Fan D, Sung SH, Witt DM, Schmelzer JR, Williams MS, Yale SH, Baumgartner C, Go AS.
The Association Between Accelerated Biological Aging and Cardiovascular Outcomes in Older Adults with Hypertension. The American journal of medicine 2024.
Abugroun A, Shah SJ, Fitzmaurice G, Hubbard C, Newman JC, Covinsky K, Fang MC.
Development of an emergency department triage tool to predict admission or discharge for older adults. International journal of emergency medicine 2025.
Abugroun A, Awadalla S, Singh S, Fang MC.
Assessing bleeding risk in patients taking anticoagulants. Journal of thrombosis and thrombolysis 2013.
Shoeb M, Fang MC.
Advanced age, anticoagulation intensity, and risk for intracranial hemorrhage among patients taking warfarin for atrial fibrillation. Annals of internal medicine 2004.
Fang MC, Chang Y, Hylek EM, Rosand J, Greenberg SM, Go AS, Singer DE.
Unexpected Heparin-Induced Thrombocytopenia While Bridging-Reply. JAMA internal medicine 2020.
Kulkarni SA, Fang MC.
Trends and Racial Differences in First Hospitalization for Stroke and 30-Day Mortality in the US Medicare Population From 1988 to 2013. Medical care 2019.
Yao J, Ghosh K, Perraillon MC, Cutler DM, Fang MC.
Performance of an online translation tool when applied to patient educational material. Journal of hospital medicine 2011.
Khanna RR, Karliner LS, Eck M, Vittinghoff E, Koenig CJ, Fang MC.
Net Clinical Benefit of Oral Anticoagulation Among Older Adults With Atrial Fibrillation. Circulation. Cardiovascular quality and outcomes 2019.
Shah SJ, Singer DE, Fang MC, Reynolds K, Go AS, Eckman MH.
Atrial fibrillation: stroke prevention in older adults. Clinics in geriatric medicine 2012.
Quinn GR, Fang MC.
Are patients more likely to see physicians of the same sex? Recent national trends in primary care medicine. The American journal of medicine 2004.
Fang MC, McCarthy EP, Singer DE.
The anticoagulation length of therapy and risk of new adverse events in venous thromboembolism (ALTERNATIVE) study: Design and survey results. PloS one 2022.
Portugal C, Fang MC, Go AS, Zhou H, Chang J, Prasad P, Fan D, Garcia EA, Sung SH, Reynolds K.
Association of Social Support With Functional Outcomes in Older Adults Who Live Alone. 2015 Year Book of Pediatrics. Ed. Cabana MD. (Elsevier; Philadelphia, PA) 2021.
Shah SJ, Fang MC, Wannier SR, Steinman MA, Covinsky KE.
Adherence to Guideline-Directed Stroke Prevention Therapy for Atrial Fibrillation Is Achievable. Circulation 2019.
Piccini JP, Xu H, Cox M, Matsouaka RA, Fonarow GC, Butler J, Curtis AB, Desai N, Fang M, McCabe PJ, Page Ii RL, Turakhia M, Russo AM, Knight BP, Sidhu M, Hurwitz JL, Ellenbogen KA, Lewis WR.
Anti-factor Xa activity assays of direct-acting oral anticoagulants during clinical care: An observational study. Research and practice in thrombosis and haemostasis 2021.
Sukumar S, Cabero M, Tiu S, Fang MC, Kogan SC, Schwartz JB.
Electronic Order Volume as a Meaningful Component in Estimating Patient Complexity and Resident Physician Workload. Journal of hospital medicine 2018.
Groningen NV, Prasad PA, Najafi N, Rajkomar A, Khanna RR, Fang MC.
Thirty-day mortality after ischemic stroke and intracranial hemorrhage in patients with atrial fibrillation on and off anticoagulants. Stroke 2012.
Fang MC, Go AS, Chang Y, Borowsky LH, Pomernacki NK, Udaltsova N, Singer DE.
Anticoagulation for atrial fibrillation. Cardiology clinics 2004.
Fang MC, Singer DE.
Time to Recognition of Sepsis in the Emergency Department Using Electronic Health Record Data: A Comparative Analysis of Systemic Inflammatory Response Syndrome, Sequential Organ Failure Assessment, and Quick Sequential Organ Failure Assessment. Critical care medicine 2020.
Prasad PA, Fang MC, Abe-Jones Y, Calfee CS, Matthay MA, Kangelaris KN.
Sex concordance between physicians and patients and discharge opioid prescribing. Journal of hospital medicine 2024.
Rambachan A, Joshi M, Auerbach AD, Fang MC.
Automated telephone follow-up programs after hospital discharge: Do older adults engage with these programs? Journal of the American Geriatrics Society 2022.
Harrison JD, Sudore RL, Auerbach AD, Shah S, Oreper S, Wheeler MM, Fang MC.
Risk factors for medication non-adherence among atrial fibrillation patients. BMC cardiovascular disorders 2019.
Reading SR, Black MH, Singer DE, Go AS, Fang MC, Udaltsova N, Harrison TN, Wei RX, Liu IA, Reynolds K.
Long-term individual and population functional outcomes in older adults with atrial fibrillation. Journal of the American Geriatrics Society 2021.
Parks AL, Jeon SY, Boscardin WJ, Steinman MA, Smith AK, Fang MC, Shah SJ.
Antithrombotic therapy for atrial fibrillation: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. Chest 2012.
You JJ, Singer DE, Howard PA, Lane DA, Eckman MH, Fang MC, Hylek EM, Schulman S, Go AS, Hughes M, Spencer FA, Manning WJ, Halperin JL, Lip GYH.
National trends in antiarrhythmic and antithrombotic medication use in atrial fibrillation. Archives of internal medicine 2004.
Fang MC, Stafford RS, Ruskin JN, Singer DE.
Health-related quali ty of life associated with warfarin and direct oral anticoagulants in venous thromboembolism. Thrombosis research 2022.
Fang MC, Go AS, Prasad PA, Zhou HX, Parks AL, Fan D, Portugal C, Sung SH, Reynolds K.
Periprocedural Bridging in Patients with Venous Thromboembolism: A Systematic Review. The American journal of medicine 2019.
Baumgartner C, de Kouchkovsky I, Whitaker E, Fang MC.
Selecting the optimal stroke prevention therapy in atrial fibrillation. Annals of internal medicine 2011.
Fang MC.
Extended Venous Thromboembolism Prophylaxis in Medically Ill Patients: An NATF Anticoagulation Action Initiative. The American journal of medicine 2020.
Barkoudah E, Piazza G, Hecht TEH, Grant P, Deitelzweig S, Fang MC, Fanikos J, Kao CK, Barnes GD, Chen T, Ramishvili T, Schnipper JL, Goldstein JN, Ruff CT, Kaatz S, Schwartz A, Connors JM, Goldhaber SZ.
Health Literacy and Treatment Satisfaction Among Patients with Venous Thromboembolism. Journal of general internal medicine 2022.
Mefford MT, Zhou H, Fan D, Fang MC, Prasad PA, Go AS, Portugal C, Chang JM, Reynolds K.
Anxiety, Depression, and Adverse Clinical Outcomes in Patients With Atrial Fibrillation Starting Warfarin: Cardiovascular Research Network WAVE Study. Journal of the American Heart Association 2018.
Baumgartner C, Fan D, Fang MC, Singer DE, Witt DM, Schmelzer JR, Williams MS, Gurwitz JH, Sung SH, Go AS.
Hazards of hospitalization: more than just "never events". Archives of internal medicine 2011.
Rennke S, Fang MC.
Association of Race and Ethnicity With Oral Anticoagulation and Associated Outcomes in Patients With Atrial Fibrillation: Findings From the Get With The Guidelines-Atrial Fibrillation Registry. JAMA cardiology 2022.
Essien UR, Chiswell K, Kaltenbach LA, Wang TY, Fonarow GC, Thomas KL, Turakhia MP, Benjamin EJ, Rodriguez F, Fang MC, Magnani JW, Yancy CW, Piccini JP.
Timing of antibiotic treatment identifies distinct clinical presentations among patients presenting with suspected septic shock. Journal of the American College of Emergency Physicians open 2024.
Prasad PA, Esmaili AM, Oreper S, Beagle AJ, Hubbard C, Raffel KE, Abe-Jones Y, Fang MC, Liu KD, Matthay MA, Kangelaris KN.
Validity of Using Inpatient and Outpatient Administrative Codes to Identify Acute Venous Thromboembolism: The CVRN VTE Study. Medical care 2017.
Fang MC, Fan D, Sung SH, Witt DM, Schmelzer JR, Steinhubl SR, Yale SH, Go AS.
A new risk scheme to predict warfarin-associated hemorrhage: The ATRIA (Anticoagulation and Risk Factors in Atrial Fibrillation) Study. Journal of the American College of Cardiology 2011.
Fang MC, Go AS, Chang Y, Borowsky LH, Pomernacki NK, Udaltsova N, Singer DE.
Letter to the Editor, The Authors Reply, "What Can Be Done to Maintain Positive Patient Experience and Improve Residents' Satisfaction?" and vStandardized Attending Rounds to Improve the Patient Experience: A Pragmatic Cluster Randomized Controlled Trial" Journal of hospital medicine 2017.
Monash B, Fang MC, Harrison J.
Incidence, management and outcomes of arterial and venous thrombosis after chimeric antigen receptor modified T cells for B cell lymphoma and multiple myeloma. Leukemia & lymphoma 2020.
Parks AL, Kambhampati S, Fakhri B, Andreadis C, Gray L, Wong SW, Shah N, Fang MC.
An NGO-Implemented Community-Clinic Health Worker Approach to Providing Long-Term Care for Hypertension in a Remote Region of Southern India. Global health, science and practice 2017.
Sankaran S, Ravi PS, Wu YE, Shanabogue S, Ashok S, Agnew K, Fang MC, Khanna RA, Dandu M, Harrison JD.
Management of atrial fibrillation in older adults. BMJ (Clinical research ed.) 2024.
Parks AL, Frankel DS, Kim DH, Ko D, Kramer DB, Lydston M, Fang MC, Shah SJ.
Anticoagulation in people with atrial fibrillation. BMJ (Clinical research ed.) 2011.
Fang MC.
Dosing Accuracy of Direct Oral Anticoagulants in an Academic Medical Center. Journal of hospital medicine 2017.
Schwartz J, Merrill S, de Leon N, Thompson A, Fang M.
The risk of venous thromboembolism with aspirin compared to anticoagulants after hip and knee arthroplasty. Thrombosis research 2017.
Chu JN, Maselli J, Auerbach AD, Fang MC.
Health Literacy and Awareness of Atrial Fibrillation. Journal of the American Heart Association 2017.
Reading SR, Go AS, Fang MC, Singer DE, Liu IA, Black MH, Udaltsova N, Reynolds K.
Women and Atrial Fibrillation. Journal of cardiovascular electrophysiology 2020.
Volgman AS, Benjamin EJ, Curtis AB, Fang MC, Lindley KJ, Naccarelli GV, Pepine CJ, Quesada O, Vaseghi M, Waldo AL, Wenger NK, Russo AM.
Warfarin discontinuation after starting warfarin for atrial fibrillation. Circulation. Cardiovascular quality and outcomes 2010.
Fang MC, Go AS, Chang Y, Borowsky LH, Pomernacki NK, Udaltsova N, Singer DE.
Warfarin Monitoring in Safety-Net Health Systems: Analysis by Race/Ethnicity and Language Preference. 2015 Year Book of Pediatrics. Ed. Cabana MD. (Elsevier; Philadelphia, PA) 2022.
Sharma AE, Khoong EC, Rivadeneira N, Sierra M, Fang MC, Gupta N, Pramanik R, Tran H, Whitezell T, Fontil V, Lee SY, Sarkar U.
Cynthia Fenton, MD
Diagnostic Errors in Hospitalized Adults Who Died or Were Transferred to Intensive Care. JAMA internal medicine 2024.
Auerbach AD, Lee TM, Hubbard CC, Ranji SR, Raffel K, Valdes G, Boscardin J, Dalal AK, Harris A, Flynn E, Schnipper JL, UPSIDE Research Group.
Relation of statin nonadherence and treatment intensification. The American journal of cardiology 2012.
Pittman DG, Fenton C, Chen W, Haffner S, Pendergrass M.
The burden of significant pain in the cirrhosis population: Risk factors, analgesic use, and impact on health care utilization and clinical outcomes. Hepatology Communications 2024.
Rubin JB, Loeb R, Fenton C, Huang CY, Keyhani S, Seal KH, Lai JC.
Exenatide and sitagliptin are not associated with increased risk of acute renal failure: a retrospective claims analysis. Diabetes, obesity & metabolism 2012.
Pendergrass M, Fenton C, Haffner SM, Chen W.
A strategy to standardize the learning of core clerkship objectives. Advances in health sciences education : theory and practice 2003.
Hauer KE, Teherani A, Wiese J, Fenton CL.
The Effect of Low-dose Aspirin on Disease Activity in Pregnant Individuals with Inflammatory Bowel Disease. The American journal of gastroenterology 2025.
Memel Z, Yu A, Fenton C, Wen T, Irani RA, Zhang L, Mahadevan U.
Intersessions: covering the bases in the clinical year. Academic medicine : journal of the Association of American Medical Colleges 2002.
Fenton C, Loeser H, Cooke M.
A retreat for first-year medicine fellows. Academic medicine : journal of the Association of American Medical Colleges 2002.
Johnston B, Fenton C, Jain S.
The type, duration, and severity of pretransplant kidney injury predict prolonged kidney dysfunction after liver transplantation. Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 2024.
Dixon W, Feng S, Roll GR, Tavakol M, Fenton C, Cullaro G.
Inflammatory Bowel Disease and the Risk of Anal Squamous Intraepithelial Lesions and Anal Cancer in Men Who Have Sex With Men. Inflammatory bowel diseases 2023.
Field J, Fenton C, Zhang L, Brickman C, Mahadevan U.
Outpatient mean arterial pressure: A potentially modifiable risk for acute kidney injury and death among cirrhosis patients. Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 2024.
Cullaro G, Chiou SH, Fenton C, Ge J, McCulloch CE, Rubin J, Shui AM, Yao F, Lai JC.