People Publications

Cigarette Smoke Exposure and ARDS in Sepsis: Epidemiology, Clinical Features, and Biologic Markers. 2015 Year Book of Pediatrics. Ed. Cabana MD. (Elsevier; Philadelphia, PA) 2022.
Moazed F, Hendrickson C, Jauregui A, Gotts J, Conroy A, Delucchi K, Zhuo H, Arambulo M, Vessel K, Ke S, Deiss T, Ni A, Leligdowicz A, Abbott J, Cohen MJ, Sinha P, Gomez A, Kangelaris K, Kornblith L, Matthay M, Benowitz N, Liu K, Calfee CS.

Building a thriving academic hospitalist workforce: A rapid qualitative analysis identifying key areas of focus in the field. Journal of hospital medicine 2023.
Kulkarni SA, Keniston A, Linker AS, Astik GJ, Kangelaris KN, Leykum LK, Sakumoto M, Auerbach A, Burden M.

Is there still a role for the lung injury score in the era of the Berlin definition ARDS? 2014.
Kangelaris KN, Calfee CS, May AK, Zhuo H, Matthay MA, Ware LB.

Implementation and evaluation of a "works-in-progress" session to promote scholarship in an academic hospitalist group. Journal of hospital medicine 2016.
Patel H, Fang MC, Harrison JD, Auerbach A, Kangelaris KN.

FGF-23 and PTH levels in patients with acute kidney injury: A cross-sectional case series study. Annals of intensive care 2011.
Zhang M, Hsu R, Hsu CY, Kordesch K, Nicasio E, Cortez A, McAlpine I, Brady S, Zhuo H, Kangelaris KN, Stein J, Calfee CS, Liu KD.

Functional Transcriptomic Studies of Immune Responses and Endotoxin Tolerance In early Human Sepsis. 2015 Year Book of Pediatrics. Ed. Cabana MD. (Elsevier; Philadelphia, PA) 2022.
Leligdowicz A, Kamm J, Kalantar K, Jauregui A, Vessel K, Caldera S, Serpa PH, Abbott J, Fang X, Tian X, Prakash A, Kangelaris KN, Liu KD, Calfee CS, Langelier C, Matthay MA.

One-year mortality and predictors of death among hospital survivors of acute respiratory distress syndrome. Intensive care medicine 2014.
Wang CY, Calfee CS, Paul DW, Janz DR, May AK, Zhuo H, Bernard GR, Matthay MA, Ware LB, Kangelaris KN.

Neighborhood Health Measured by the Healthy Places Index (HPI), but Not by the Area Deprivation Index (ADI), Is Associated With Mortality for Critically Ill Sepsis Patients in the San Francisco Bay Area. American journal of respiratory and critical care medicine 2025.
K.M. Sullivan, A.M. Dedent, A. Willmore, K.N. Kangelaris, C.M. Hendrickson, C. Lin, C.S. Calfee, N. Thakur, M.A. Matthay.

Longitudinal multiomic signatures of ARDS and sepsis inflammatory phenotypes identify pathways associated with mortality. The Journal of clinical investigation 2025.
Alipanah-Lechner N, Neyton L, Sinha P, Leroux C, Bardillon K, Carrillo SA, Chak S, Chao O, Hariharan T, Hendrickson C, Kangelaris K, Langelier CR, Lee D, Lin C, Liu K, Magee L, Ringor A, Sarma A, Schmiege E, Spottiswoode N, Sullivan K, Weingart MF, Willmore A, Zhuo H, Rogers AJ, Stringer KA, Matthay MA, Calfee CS.

Genetic Testing Before Anticoagulation? A Systematic Review of Pharmacogenetic Dosing of Warfarin. Journal of general internal medicine 2009.
Kirsten Neudoerffer Kangelaris, Stephen Bent, Robert L. Nussbaum, David A. Garcia, Jeffrey A. Tice.

Validation and utility of ARDS subphenotypes identified by machine-learning models using clinical data: an observational, multicohort, retrospective analysis. 2015 Year Book of Pediatrics. Ed. Cabana MD. (Elsevier; Philadelphia, PA) 2022.
Maddali MV, Churpek M, Pham T, Rezoagli E, Zhuo H, Zhao W, He J, Delucchi KL, Wang C, Wickersham N, McNeil JB, Jauregui A, Ke S, Vessel K, Gomez A, Hendrickson CM, Kangelaris KN, Sarma A, Leligdowicz A, Liu KD, Matthay MA, Ware LB, Laffey JG, Bellani G, Calfee CS, Sinha P, LUNG SAFE Investigators and the ESICM Trials Group.

Association between a serotonin transporter gene variant and hopelessness among men in the Heart and Soul Study. Journal of general internal medicine 2010.
Kangelaris KN, Vittinghoff E, Otte C, Na B, Auerbach AD, Whooley MA.

Vasopressor Duration and Intensity Differs by Inflammatory Subphenotype in Sepsis. American journal of respiratory and critical care medicine 2025.
P.A. Sanchez, N. Alipanah-Lechner, C.M. Hendrickson, K.N. Kangelaris, C. Lin, L. Magee, O. Chao, S. Chak, K. Bardillon, M.A. Matthay, A. Rogers, C.S. Calfee.

Acute Respiratory Distress Syndrome Molecular Phenotypes Have Distinct Lower Respiratory Tract Transcriptomes. American journal of respiratory and critical care medicine 2025.
Sarma A, Christenson SA, Shoshana BZ, Oliveira AP, Neyton LPA, Mick E, Sinha P, Wilson JG, Moazed F, Leligdowicz A, Maddali MV, Siegel ER, Lyon ZM, Carrillo SH, Zhou H, Jauregui A, Ghale R, Caldera S, Hayakawa PS, Deiss T, Love C, Byrne A, Kalantar KL, DeRisi JL, Erle DJ, Krummel MF, Kangelaris KN, Hendrickson CM, Woodruff PG, Matthay MA, Bos LDJ, Langelier CR, Calfee CS, COMET Consortium.

Host and Microbe Blood Metagenomics Reveals Key Pathways Characterizing Critical Illness Phenotypes. American journal of respiratory and critical care medicine 2024.
Neyton LPA, Sinha P, Sarma A, Mick E, Kalantar K, Chen S, Wu N, Delucchi K, Zhuo H, Bos LDJ, Jauregui A, Gomez A, Hendrickson CM, Kangelaris KN, Leligdowicz A, Liu KD, Matthay MA, Langelier CR, Calfee CS.

Distinct pulmonary and systemic effects of dexamethasone in severe COVID-19. Nature communications 2024.
Neyton LPA, Patel RK, Sarma A, UCSF COMET Consortium, Willmore A, Haller SC, Kangelaris KN, Eckalbar WL, Erle DJ, Krummel MF, Hendrickson CM, Woodruff PG, Langelier CR, Calfee CS, Fragiadakis GK.

Genetic testing before anticoagulation? A systematic review of pharmacogenetic dosing of warfarin. Journal of general internal medicine 2009.
Kangelaris KN, Bent S, Nussbaum RL, Garcia DA, Tice JA.

Mass cytometry reveals a conserved immune trajectory of recovery in hospitalized COVID-19 patients. Immunity 2022.
Burnett CE, Okholm TLH, Tenvooren I, Marquez DM, Tamaki S, Munoz Sandoval P, Willmore A, UCSF COMET Consortium, Hendrickson CM, Kangelaris KN, Langelier CR, Krummel MF, Woodruff PG, Calfee CS, Erle DJ, Ansel KM, Spitzer MH.

Increased rates of secondary bacterial infections, including Enterococcus bacteremia, in patients hospitalized with coronavirus disease 2019 (COVID-19). Infection control and hospital epidemiology 2021.
DeVoe C, Segal MR, Wang L, Stanley K, Madera S, Fan J, Schouest J, Graham-Ojo R, Nichols A, Prasad PA, Ghale R, Love C, Abe-Jones Y, Kangelaris KN, Patterson SL, Yokoe DS, Langelier CR.

Prognostic Relevance of Inflammatory Subphenotypes in Immunocompromised Patients With Sepsis. Critical care medicine 2025.
Weingart MF, Willmore A, Zhuo H, Magee L, Chao O, Lin C, Schmiege E, Hariharan T, Chak S, Bardillon K, Lee D, Leroux C, Obeidalla SN, Kerchberger VE, Sullivan K, Langelier C, Hendrickson CM, Kangelaris KN, Sarma A, Evrard B, Alipanah-Lechner N, Sinha P, Matthay MA, Ware LB, Calfee CS.

Causes and attributable fraction of death from ARDS in inflammatory phenotypes of sepsis. Critical care (London, England) 2024.
Evrard B, Sinha P, Delucchi K, Hendrickson CM, Kangelaris KN, Liu KD, Willmore A, Wu N, Neyton L, Schmiege E, Gomez A, Kerchberger VE, Zalucky A, Matthay MA, Ware LB, Calfee CS.

Clinical implications of founder and recurrent CDH1 mutations in hereditary diffuse gastric cancer. JAMA 2007.
Kangelaris KN, Gruber SB.

Increased risk of severe clinical course of COVID-19 in carriers of HLA-C*04:01. EClinicalMedicine 2021.
Weiner J, Suwalski P, Holtgrewe M, Rakitko A, Thibeault C, Müller M, Patriki D, Quedenau C, Krüger U, Ilinsky V, Popov I, Balnis J, Jaitovich A, Helbig ET, Lippert LJ, Stubbemann P, Real LM, Macías J, Pineda JA, Fernandez-Fuertes M, Wang X, Karadeniz Z, Saccomanno J, Doehn JM, Hübner RH, Hinzmann B, Salvo M, Blueher A, Siemann S, Jurisic S, Beer JH, Rutishauser J, Wiggli B, Schmid H, Danninger K, Binder R, Corman VM, Mühlemann B, Arjun Arkal R, Fragiadakis GK, Mick E, Comet C, Calfee CS, Erle DJ, Hendrickson CM, Kangelaris KN, Krummel MF, Woodruff PG, Langelier CR, Venkataramani U, García F, Zyla J, Drosten C, Alice B, Jones TC, Suttorp N, Witzenrath M, Hippenstiel S, Zemojtel T, Skurk C, Wolfgang P, Borodina T, Pa-Covid SG, Ripke S, Sander LE, Beule D, Landmesser U, Guettouche T, Kurth F, Heidecker B.

Type 2 immune responses are associated with less severe COVID-19 in a hospitalized cohort. The journal of allergy and clinical immunology. Global 2025.
Jayavelu ND, Qi J, Milliren CE, Ozonoff A, Liu S, Levy O, Baden LR, Melamed E, McComsey GA, Cairns CB, Schaenman J, Shaw AC, Hafler DA, Corry DB, Kheradmand F, Atkinson MA, Brakenridge SC, Agudelo Higuita NI, Metcalf JP, Hough CL, Messer WB, Pulendran B, Nadeau KC, Davis MM, Geng LN, Sesma AF, Simon V, Krammer F, Bime C, Calfee CS, Bosinger SE, Eckalbar W, Steen H, Maecker HT, IMPACC Network, Augustine AD, Diray-Arce J, Haddad EK, Sekaly RP, Kraft M, Woodruff PG, Erle DJ, Ehrlich LIR, Montgomery RR, Becker PM, Altman MC, Fourati S.

Rapidly improving ARDS differs clinically and biologically from persistent ARDS. Critical care (London, England) 2024.
Valda Toro PL, Willmore A, Wu NE, Delucchi KL, Jauregui A, Sinha P, Liu KD, Hendrickson CM, Sarma A, Neyton LPA, Leligdowicz A, Langelier CR, Zhuo H, Jones C, Kangelaris KN, Gomez AD, Matthay MA, Calfee CS.

Host-microbe multiomic profiling reveals age-dependent immune dysregulation associated with COVID-19 immunopathology. Science translational medicine 2024.
Phan HV, Tsitsiklis A, Maguire CP, Haddad EK, Becker PM, Kim-Schulze S, Lee B, Chen J, Hoch A, Pickering H, van Zalm P, Altman MC, Augustine AD, Calfee CS, Bosinger S, Cairns CB, Eckalbar W, Guan L, Jayavelu ND, Kleinstein SH, Krammer F, Maecker HT, Ozonoff A, Peters B, Rouphael N, IMPACC Network, Montgomery RR, Reed E, Schaenman J, Steen H, Levy O, Diray-Arce J, Langelier CR.

Associations Between Volume of Early Intravenous Fluid and Hospital Outcomes in Septic Patients With and Without Heart Failure: A Retrospective Cohort Study. Critical care explorations 2024.
Beagle AJ, Prasad PA, Hubbard CC, Walderich S, Oreper S, Abe-Jones Y, Fang MC, Kangelaris KN.

Elevated Hemoglobin A1c and the Risk of Developing ARDS in Two Cohort Studies. CHEST Critical Care 2024.
Bogart AM, Lopez CR, Obeidalla SN, Wang C, Willmore A, Jauregui A, Kangelaris KN, Hendrickson C, Gomez A, Liu KD, Matthay MA, Shaver CM, Bastarache JA, Calfee CS, Kerchberger VE, Ware LB.

Upper airway gene expression reveals suppressed immune responses to SARS-CoV-2 compared with other respiratory viruses. Nature communications 2020.
Mick E, Kamm J, Pisco AO, Ratnasiri K, Babik JM, Castañeda G, DeRisi JL, Detweiler AM, Hao SL, Kangelaris KN, Kumar GR, Li LM, Mann SA, Neff N, Prasad PA, Serpa PH, Shah SJ, Spottiswoode N, Tan M, Calfee CS, Christenson SA, Kistler A, Langelier C.

Tracheal aspirate RNA sequencing identifies distinct immunological features of COVID-19 ARDS. Nature communications 2021.
Sarma A, Christenson SA, Byrne A, Mick E, Pisco AO, DeVoe C, Deiss T, Ghale R, Zha BS, Tsitsiklis A, Jauregui A, Moazed F, Detweiler AM, Spottiswoode N, Sinha P, Neff N, Tan M, Serpa PH, Willmore A, Ansel KM, Wilson JG, Leligdowicz A, Siegel ER, Sirota M, DeRisi JL, Matthay MA, COMET Consortium , Hendrickson CM, Kangelaris KN, Krummel MF, Woodruff PG, Erle DJ, Calfee CS, Langelier CR.

Adaptability on Shifting Ground: a Rapid Qualitative Assessment of Multi-institutional Inpatient Surge Planning and Workforce Deployment During the COVID-19 Pandemic. 2015 Year Book of Pediatrics. Ed. Cabana MD. (Elsevier; Philadelphia, PA) 2022.
Keniston A, Sakumoto M, Astik GJ, Auerbach A, Eid SM, Kangelaris KN, Kulkarni SA, Lee T, Leykum LK, Linker AS, Worster DT, Burden M.

A conserved immune trajectory of recovery in hospitalized COVID-19 patients. 2015 Year Book of Pediatrics. Ed. Cabana MD. (Elsevier; Philadelphia, PA) 2022.
Burnett CE, Hauge Okholm TL, Tenvooren I, Marquez DM, Tamaki S, Sandoval PM, UCSF COMET Consortium, Calfee CS, Hendrickson CM, Kangelaris KN, Langelier CR, Krummel MF, Woodruff PG, Erle DJ, Ansel KM, Spitzer MH.

Type I interferon autoantibodies are associated with systemic immune alterations in patients with COVID-19. Science translational medicine 2021.
van der Wijst MGP, Vazquez SE, Hartoularos GC, Bastard P, Grant T, Bueno R, Lee DS, Greenland JR, Sun Y, Perez R, Ogorodnikov A, Ward A, Mann SA, Lynch KL, Yun C, Havlir DV, Chamie G, Marquez C, Greenhouse B, Lionakis MS, Norris PJ, Dumont LJ, Kelly K, Zhang P, Zhang Q, Gervais A, Le Voyer T, Whatley A, Si Y, Byrne A, Combes AJ, Rao AA, Song YS, Fragiadakis GK, Kangelaris K, Calfee CS, Erle DJ, Hendrickson C, Krummel MF, Woodruff PG, Langelier CR, Casanova JL, Derisi JL, Anderson MS, Ye CJ, UCSF COMET consortium.

Agreement Between Sepsis-2 and Sepsis-3 Definitions Among Patients Admitted to the Intensive Care Unit. Annals of the American Thoracic Society 2024.
Zalucky AA, Evrard B, Delucchi K, Zhuo H, Wu N, Liu KD, Hendrickson CM, Matthay MA, Kangelaris KN, Calfee CS.

Latent class analysis-derived subphenotypes are generalisable to observational cohorts of acute respiratory distress syndrome: a prospective study. Thorax 2021.
Sinha P, Delucchi KL, Chen Y, Zhuo H, Abbott J, Wang C, Wickersham N, McNeil JB, Jauregui A, Ke S, Vessel K, Gomez A, Hendrickson CM, Kangelaris KN, Sarma A, Leligdowicz A, Liu KD, Matthay MA, Ware LB, Calfee CS.

Efficacy and safety of two neutralising monoclonal antibody therapies, sotrovimab and BRII-196 plus BRII-198, for adults hospitalised with COVID-19 (TICO): a randomised controlled trial. 2015 Year Book of Pediatrics. Ed. Cabana MD. (Elsevier; Philadelphia, PA) 2021.
ACTIV-3/Therapeutics for Inpatients with COVID-19 (TICO) Study Group.

Therapeutic Anticoagulation with Heparin in Critically Ill Patients with Covid-19. The New England journal of medicine 2021.
REMAP-CAP Investigators , ACTIV-4a Investigators , ATTACC Investigators , Goligher EC, Bradbury CA, McVerry BJ, Lawler PR, Berger JS, Gong MN, Carrier M, Reynolds HR, Kumar A, Turgeon AF, Kornblith LZ, Kahn SR, Marshall JC, Kim KS, Houston BL, Derde LPG, Cushman M, Tritschler T, Angus DC, Godoy LC, McQuilten Z, Kirwan BA, Farkouh ME, Brooks MM, Lewis RJ, Berry LR, Lorenzi E, Gordon AC, Ahuja T, Al-Beidh F, Annane D, Arabi YM, Aryal D, Baumann Kreuziger L, Beane A, Bhimani Z, Bihari S, Billett HH, Bond L, Bonten M, Brunkhorst F, Buxton M, Buzgau A, Castellucci LA, Chekuri S, Chen JT, Cheng AC, Chkhikvadze T, Coiffard B, Contreras A, Costantini TW, de Brouwer S, Detry MA, Duggal A, Džavík V, Effron MB, Eng HF, Escobedo J, Estcourt LJ, Everett BM, Fergusson DA, Fitzgerald M, Fowler RA, Froess JD, Fu Z, Galanaud JP, Galen BT, Gandotra S, Girard TD, Goodman AL, Goossens H, Green C, Greenstein YY, Gross PL, Haniffa R, Hegde SM, Hendrickson CM, Higgins AM, Hindenburg AA, Hope AA, Horowitz JM, Horvat CM, Huang DT, Hudock K, Hunt BJ, Husain M, Hyzy RC, Jacobson JR, Jayakumar D, Keller NM, Khan A, Kim Y, Kindzelski A, King AJ, Knudson MM, Kornblith AE, Kutcher ME, Laffan MA, Lamontagne F, Le Gal G, Leeper CM, Leifer ES, Lim G, Gallego Lima F, Linstrum K, Litton E, Lopez-Sendon J, Lother SA, Marten N, Saud Marinez A, Martinez M, Mateos Garcia E, Mavromichalis S, McAuley DF, McDonald EG, McGlothlin A, McGuinness SP, Middeldorp S, Montgomery SK, Mouncey PR, Murthy S, Nair GB, Nair R, Nichol AD, Nicolau JC, Nunez-Garcia B, Park JJ, Park PK, Parke RL, Parker JC, Parnia S, Paul JD, Pompilio M, Quigley JG, Rosenson RS, Rost NS, Rowan K, Santos FO, Santos M, Santos MO, Satterwhite L, Saunders CT, Schreiber J, Schutgens REG, Seymour CW, Siegal DM, Silva DG, Singhal AB, Slutsky AS, Solvason D, Stanworth SJ, Turner AM, van Bentum-Puijk W, van de Veerdonk FL, van Diepen S, Vazquez-Grande G, Wahid L, Wareham V, Widmer RJ, Wilson JG, Yuriditsky E, Zhong Y, Berry SM, McArthur CJ, Neal MD, Hochman JS, Webb SA, Zarychanski R.

Early plasma angiopoietin-2 is prognostic for ARDS and mortality among critically ill patients with sepsis. Critical care (London, England) 2023.
Rosenberger CM, Wick KD, Zhuo H, Wu N, Chen Y, Kapadia SB, Guimaraes A, Chang D, Choy DF, Chen H, Peck M, Sullivan KM, Ke S, Jauregui A, Leligdowicz A, Sinha P, Gomez AD, Kangelaris KN, Delucchi K, Liu KD, Calfee CS, Matthay MA, Hendrickson CM.

A myeloid program associated with COVID-19 severity is decreased by therapeutic blockade of IL-6 signaling. iScience 2023.
Hackney JA, Shivram H, Vander Heiden J, Overall C, Orozco L, Gao X, Kim E, West N, Qamra A, Chang D, Chakrabarti A, Choy DF, Combes AJ, Courau T, Fragiadakis GK, Rao AA, Ray A, Tsui J, Hu K, Kuhn NF, Krummel MF, Erle DJ, Kangelaris K, Sarma A, Lyon Z, Calfee CS, Woodruff PG, Ghale R, Mick E, Byrne A, Zha BS, Langelier C, Hendrickson CM, van der Wijst MGP, Hartoularos GC, Grant T, Bueno R, Lee DS, Greenland JR, Sun Y, Perez R, Ogorodnikov A, Ward A, Ye CJ, UCSF COMET Consortium, Ramalingam T, McBride JM, Cai F, Teterina A, Bao M, Tsai L, Rosas IO, Regev A, Kapadia SB, Bauer RN, Rosenberger CM.

Microbial dynamics and pulmonary immune responses in COVID-19 secondary bacterial pneumonia. Nature communications 2024.
Spottiswoode N, Tsitsiklis A, Chu VT, Phan HV, DeVoe C, Love C, Ghale R, Bloomstein J, Zha BS, Maguire CP, Glascock A, Sarma A, Mourani PM, Kalantar KL, Detweiler A, Neff N, Haller SC, COMET Consortium, DeRisi JL, Erle DJ, Hendrickson CM, Kangelaris KN, Krummel MF, Matthay MA, Woodruff PG, Calfee CS, Langelier CR.

Variation in Initial U.S. Hospital Responses to the Coronavirus Disease 2019 Pandemic. Critical care medicine 2021.
Mathews KS, Seitz KP, Vranas KC, Duggal A, Valley TS, Zhao B, Gundel S, Harhay MO, Chang SY, Hough CL, National Heart, Lung, and Blood Institute Prevention and Early Treatment of Acute Lung Injury (PETAL.

Responses to a Neutralizing Monoclonal Antibody for Hospitalized Patients With COVID-19 According to Baseline Antibody and Antigen Levels : A Randomized Controlled Trial. 2015 Year Book of Pediatrics. Ed. Cabana MD. (Elsevier; Philadelphia, PA) 2021.
ACTIV-3/TICO Bamlanivimab Study Group, Lundgren JD, Grund B, Barkauskas CE, Holland TL, Gottlieb RL, Sandkovsky U, Brown SM, Knowlton KU, Self WH, Files DC, Jain MK, Benfield T, Bowdish ME, Leshnower BG, Baker JV, Jensen JU, Gardner EM, Ginde AA, Harris ES, Johansen IS, Markowitz N, Matthay MA, Østergaard L, Chang CC, Goodman AL, Chang W, Dewar RL, Gerry NP, Higgs ES, Highbarger H, Murray DD, Murray TA, Natarajan V, Paredes R, Parmar MKB, Phillips AN, Reilly C, Rupert AW, Sharma S, Shaw-Saliba K, Sherman BT, Teitelbaum M, Wentworth D, Cao H, Klekotka P, Babiker AG, Davey VJ, Gelijns AC, Kan VL, Polizzotto MN, Thompson BT, Lane HC, Neaton JD.

Publisher Correction: Global absence and targeting of protective immune states in severe COVID-19. Nature 2021.
Combes AJ, Courau T, Kuhn NF, Hu KH, Ray A, Chen WS, Chew NW, Cleary SJ, Kushnoor D, Reeder GC, Shen A, Tsui J, Hiam-Galvez KJ, Muñoz-Sandoval P, Zhu WS, Lee DS, Sun Y, You R, Magnen M, Rodriguez L, Im KW, Serwas NK, Leligdowicz A, Zamecnik CR, Loudermilk RP, Wilson MR, Ye CJ, Fragiadakis GK, Looney MR, Chan V, Ward A, Carrillo S, UCSF COMET Consortium , Matthay M, Erle DJ, Woodruff PG, Langelier C, Kangelaris K, Hendrickson CM, Calfee C, Rao AA, Krummel MF.

Distinct pulmonary and systemic effects of dexamethasone in severe COVID-19. Research square 2023.
Fragiadakis G, Neyton L, Patel R, Sarma A, Consortium UC, Willmore A, Haller SC, Kangelaris K, Eckalbar W, Erle D, Krummel M, Hendrickson C, Woodruff P, Langelier C, Calfee C.

Impaired immune signaling and changes in the lung microbiome precede secondary bacterial pneumonia in COVID-19. Research square 2021.
Tsitsiklis A, Zha B, Byrne A, DeVoe C, Levan S, Rackaityte E, Sunshine S, Mick E, Ghale R, Jauregui A, Neff N, Sarma A, Serpa P, Deiss T, Kistler A, Carrillo S, Ansel KM, Leligdowicz A, Christenson S, Jones N, Wu B, Darmanis S, Matthay M, Lynch S, DeRisi J, Consortium C, Hendrickson C, Kangelaris K, Krummel M, Woodruff P, Erle D, Rosenberg O, Calfee C, Langelier C.

A Neutralizing Monoclonal Antibody for Hospitalized Patients with Covid-19. The New England journal of medicine 2020.
ACTIV-3/TICO LY-CoV555 Study Group , Lundgren JD, Grund B, Barkauskas CE, Holland TL, Gottlieb RL, Sandkovsky U, Brown SM, Knowlton KU, Self WH, Files DC, Jain MK, Benfield T, Bowdish ME, Leshnower BG, Baker JV, Jensen JU, Gardner EM, Ginde AA, Harris ES, Johansen IS, Markowitz N, Matthay MA, Østergaard L, Chang CC, Davey VJ, Goodman A, Higgs ES, Murray DD, Murray TA, Paredes R, Parmar MKB, Phillips AN, Reilly C, Sharma S, Dewar RL, Teitelbaum M, Wentworth D, Cao H, Klekotka P, Babiker AG, Gelijns AC, Kan VL, Polizzotto MN, Thompson BT, Lane HC, Neaton JD.

Plasma Metabolites in Early Sepsis Identify Distinct Clusters Defined by Plasma Lipids. Critical care explorations 2021.
Rogers AJ, Leligdowicz A, Contrepois K, Jauregui A, Vessel K, Deiss TJ, Belzer A, Liu T, Lippi M, Ke S, Ross E, Zhou H, Hendrickson C, Gomez A, Sinha P, Kangelaris KN, Liu KD, Calfee CS, Matthay MA.

Using best subset regression to identify clinical characteristics and biomarkers associated with sepsis-associated acute kidney injury. American journal of physiology. Renal physiology 2020.
Kwong YD, Mehta KM, Miaskowski C, Zhuo H, Yee K, Jauregui A, Ke S, Deiss T, Abbott J, Kangelaris KN, Sinha P, Hendrickson C, Gomez A, Leligdowicz A, Matthay MA, Calfee CS, Liu KD.

Clinician Recognition of the Acute Respiratory Distress Syndrome: Risk Factors for Under-Recognition and Trends Over Time. Critical care medicine 2020.
Schwede M, Lee RY, Zhuo H, Kangelaris KN, Jauregui A, Vessel K, Belzer A, Deiss T, Matthay MA, Liu KD, Calfee CS.

Acute respiratory distress syndrome-attributable mortality in critically ill patients with sepsis. Intensive care medicine 2020.
Auriemma CL, Zhuo H, Delucchi K, Deiss T, Liu T, Jauregui A, Ke S, Vessel K, Lippi M, Seeley E, Kangelaris KN, Gomez A, Hendrickson C, Liu KD, Matthay MA, Ware LB, Calfee CS.

Identifying and Measuring Administrative Harms Experienced by Hospitalists and Administrative Leaders. JAMA internal medicine 2024.
Burden M, Astik G, Auerbach A, Bowling G, Kangelaris KN, Keniston A, Kochar A, Leykum LK, Linker AS, Sakumoto M, Rogers K, Schwatka N, Westergaard S.

Peripheral blood leukocyte telomere length is associated with survival of sepsis patients. The European respiratory journal 2020.
Liu S, Wang C, Green G, Zhuo H, Liu KD, Kangelaris KN, Gomez A, Jauregui A, Vessel K, Ke S, Hendrickson C, Matthay MA, Calfee CS, Ware LB, Wolters PJ.

Shared Decision-Making During Inpatient Rounds: Opportunities for Improvement in Patient Engagement and Communication. Journal of hospital medicine 2018.
Blankenburg R, Hilton JF, Yuan P, Rennke S, Monash B, Harman SM, Sakai DS, Hosamani P, Khan A, Chua I, Huynh E, Shieh L, Xie L.

The Importance of Emotional Intelligence When Leading in a Time of Crisis. Journal of hospital medicine 2020.
Kantor MA, Apgar SK, Esmaili AM, Khan A, Monash B, Sharpe BA.

The SDM 3 Circle Model: A Literature Synthesis and Adaptation for Shared Decision Making in the Hospital. Journal of hospital medicine 2017.
Rennke S, Yuan P, Monash B, Blankenburg R, Chua I, Harman S, Sakai DS, Khan A, Hilton JF, Shieh L, Satterfield J.

Protecting reproductive health information in the post-Roe era: interoperability strategies for healthcare institutions. Journal of the American Medical Informatics Association : JAMIA 2022.
Khanna RR, Murray SG, Wen T, Salmeen K, Illangasekare T, Benfield N, Adler-Milstein J, Savage L.

Predictive value of the present-on-admission indicator for hospital-acquired venous thromboembolism. Medical care 2015.
Khanna RR, Kim SB, Jenkins I, El-Kareh R, Afsarmanesh N, Amin A, Sand H, Auerbach A, Chia CY, Maynard G, Romano PS, White RH.

Completeness and quality of text paging for subspecialty consult requests. Postgraduate medical journal 2020.
Chu CD, Tuot DS, Harrison JD, Duong J, Luxenberg A, Khanna RR.

All That Beeps is Not Urgent: Hospitalist and Nurse Concordance of Assigning Priority Classification to Pages. Journal of general internal medicine 2024.
Flynn SJ, Hsiang EY, Kantor MA, Rao MN, Khanna R.

Clinical implementation of preemptive pharmacogenomics testing for personalized medicine at an academic medical center. Journal of the American Medical Informatics Association : JAMIA 2024.
Tamraz B, Shin J, Khanna R, Van Ziffle J, Knowles S, Stregowski S, Wan E, Kamath R, Collins C, Phunsur C, Tsai B, Kong P, Calanoc C, Pollard A, Sawhney R, Pleiman J, Devine WP, Croci R, Sashikanth A, Kroon L, Cucina R, Rajkovic A.

Enhancing Health Care Communication With Large Language Models-The Role, Challenges, and Future Directions. JAMA network open 2024.
Raghu Subramanian C, Yang DA, Khanna R.

Letting a Good Crisis Go to Waste. Journal of general internal medicine 2019.
Auerbach AD, Khanna R, Adler-Milstein J.

Simulating Strategies for Improving Control of Hypertension Among Patients with Usual Source of Care in the United States: The Blood Pressure Control Model. Journal of general internal medicine 2015.
Fontil V, Bibbins-Domingo K, Kazi DS, Sidney S, Coxson PG, Khanna R, Victor RG, Pletcher MJ.

An automated telephone nutrition support system for Spanish-speaking patients with diabetes. Journal of diabetes science and technology 2014.
Khanna R, Stoddard PJ, Gonzales EN, Villagran-Flores M, Thomson J, Bayard P, Palos Lucio AG, Schillinger D, Bertozzi S, Gonzales R.

A Systematic Approach to the Design and Implementation of Clinical Informatics Fellowship Programs. Applied clinical informatics 2023.
Lingham V, Chandwarkar A, Miller M, Baker C, Genes N, Hellems M, Khanna R, Mize D, Silverman H.

The Best Laid Plans-Medication Reconciliation Optimization in Theory and Practice. Journal of hospital medicine 2019.
Jue VI, Khanna RR.

Tablet computers for hospitalized patients: a pilot study to improve inpatient engagement. Journal of hospital medicine 2014.
Greysen SR, Khanna RR, Jacolbia R, Lee HM, Auerbach AD.

Effectiveness of a Best Practice Alert to Reduce Telemetry Orders-Reply. JAMA internal medicine 2019.
Najafi N, Cucina R, Khanna R.

A single center evaluation of applicant experiences in virtual interviews across eight internal medicine subspecialty fellowship programs. Medical education online 2021.
Huppert LA, Hsu G, Elnachef N, Flint L, Frank JA, Gensler LS, Hsiao EC, Khanna RR, Qasim A, Schwartz BS, Widera E, Zapata C, Babik JM.

Incidence of hospital-acquired venous thromboembolic codes in medical patients hospitalized in academic medical centers. Journal of hospital medicine 2014.
Khanna R, Maynard G, Sadeghi B, Hensley L, Medvedev S, Danielsen B, White RH.

Governance of Electronic Health Record Modification at US Academic Medical Centers. Applied clinical informatics 2023.
Ravi A, Arvisais-Anhalt S, Weia B, Khanna R, Adler-Milstein J, Auerbach AD.

The Elements of Style for Interruptive Electronic Health Record Alerts. Applied clinical informatics 2024.
Pourian J, Subramanian C, Blebea C, Auerbach AD, Khanna R.

Predictive value of the present-on-admission indicator for hospital-associated hemorrhage. Thrombosis research 2019.
Ghazvinian R, White RH, Gage BF, Fang MC, Saeed R, Khanna RR.

Internal medicine rounding practices and the Accreditation Council for Graduate Medical Education core competencies. Journal of hospital medicine 2014.
Shoeb M, Khanna R, Fang M, Sharpe B, Finn K, Ranji S, Monash B.

Differences in Narrative Language in Evaluations of Medical Students by Gender and Under-represented Minority Status. Journal of general internal medicine 2019.
Rojek AE, Khanna R, Yim JWL, Gardner R, Lisker S, Hauer KE, Lucey C, Sarkar U.

Computerized physician order entry: promise, perils, and experience. The Neurohospitalist 2014.
Khanna R, Yen T.

Assessment of a Targeted Electronic Health Record Intervention to Reduce Telemetry Duration: A Cluster-Randomized Clinical Trial. JAMA internal medicine 2019.
Najafi N, Cucina R, Pierre B, Khanna R.

Physician underutilization of effective medications for resistant hypertension at office visits in the United States: NAMCS 2006-2010. Journal of general internal medicine 2013.
Fontil V, Pletcher MJ, Khanna R, Guzman D, Victor R, Bibbins-Domingo K.

Using Technology to Enhance Communication. The Medical clinics of North America 2022.
Sakumoto M, Khanna R.

Missed opportunities for treatment of uncontrolled hypertension at physician office visits in the United States, 2005 through 2009. Archives of internal medicine 2012.
Khanna RR, Victor RG, Bibbins-Domingo K, Shapiro MF, Pletcher MJ.

Behavioral "nudges" in the electronic health record to reduce waste and misuse: 3 interventions. Journal of the American Medical Informatics Association : JAMIA 2022.
Grouse CK, Waung MW, Holmgren AJ, Mongan J, Neinstein A, Josephson SA, Khanna RR.

Balancing Innovation and Safety When Integrating Digital Tools Into Health Care. Annals of internal medicine 2018.
Auerbach AD, Neinstein A, Khanna R.

Performance of an online translation tool when applied to patient educational material. Journal of hospital medicine 2011.
Khanna RR, Karliner LS, Eck M, Vittinghoff E, Koenig CJ, Fang MC.

Just-in-Time Digital Health Interventions-Start of a New Era With Much More to Do. JAMA internal medicine 2023.
Khanna R, Auerbach A.

Electronic Order Volume as a Meaningful Component in Estimating Patient Complexity and Resident Physician Workload. Journal of hospital medicine 2018.
Groningen NV, Prasad PA, Najafi N, Rajkomar A, Khanna RR, Fang MC.

Unintended consequences of a standard admission order set on venous thromboembolism prophylaxis and patient outcomes. Journal of general internal medicine 2011.
Khanna R, Vittinghoff E, Maselli J, Auerbach A.

"Nebs no more after 24": a pilot program to improve the use of appropriate respiratory therapies. JAMA internal medicine 2013.
Moriates C, Novelero M, Quinn K, Khanna R, Mourad M.

Balancing Innovation and Safety When Integrating Digital Tools Into Health Care. Annals of internal medicine 2018.
Auerbach AD, Neinstein A, Khanna R.

The association between night or weekend admission and hospitalization-relevant patient outcomes. Journal of hospital medicine 2010.
Khanna R, Wachsberg K, Marouni A, Feinglass J, Williams MV, Wayne DB.

The Launch of the iCoDE Standard Project. Journal of diabetes science and technology 2022.
Xu NY, Nguyen KT, DuBord AY, Klonoff DC, Goldman JM, Shah SN, Spanakis EK, Madlock-Brown C, Sarlati S, Rafiq A, Wirth A, Kerr D, Khanna R, Weinstein S, Espinoza J.

An NGO-Implemented Community-Clinic Health Worker Approach to Providing Long-Term Care for Hypertension in a Remote Region of Southern India. Global health, science and practice 2017.
Sankaran S, Ravi PS, Wu YE, Shanabogue S, Ashok S, Agnew K, Fang MC, Khanna RA, Dandu M, Harrison JD.

Designing and Implementing a Novel Virtual Rounds Curriculum for Medical Students' Internal Medicine Clerkship During the COVID-19 Pandemic. MedEdPORTAL : the journal of teaching and learning resources 2021.
Sukumar S, Zakaria A, Lai CJ, Sakumoto M, Khanna R, Choi N.

Using Spatial and Temporal Mapping to Identify Nosocomial Disease Transmission of Clostridium difficile. JAMA internal medicine 2017.
Murray SG, Yim JWL, Croci R, Rajkomar A, Schmajuk G, Khanna R, Cucina RJ.

Industry Electives in Clinical Informatics Fellowship: Early Experiences from a Multi-Institution Survey. Applied clinical informatics 2026.
Genes N, Solanki P, Kannry J, Khanna R, Mize D, Lingam V, Turer RW, Leu MG.

Cultivating AI leaders: the role of clinical informatics fellowship in transforming healthcare. Lancet regional health. Americas 2026.
Lingam V, Kannry J, Khanna R, Norquist C, Leu MG, Hron JD.

Characterizing the Source of Text in Electronic Health Record Progress Notes. JAMA internal medicine 2017.
Wang MD, Khanna R, Najafi N.

Efficiency and Interpretability of Text Paging Communication for Medical Inpatients: A Mixed-Methods Analysis. JAMA internal medicine 2017.
Luxenberg A, Chan B, Khanna R, Sarkar U.

Automating Venous Thromboembolism Risk Calculation Using Electronic Health Record Data upon Hospital Admission: The Automated Padua Prediction Score. Journal of hospital medicine 2017.
Elias P, Khanna R, Dudley A, Davies J, Jacolbia R, McArthur K, Auerbach AD.

The emerging role of clinical informatics fellows in service learning during the COVID-19 pandemic. Journal of the American Medical Informatics Association : JAMIA 2020.
Subash M, Sakumoto M, Bass J, Hong P, Muniyappa A, Pierce L, Purmal C, Ramaswamy P, Sono R, Uptegraft C, Feinstein D, Khanna R.

Impact of standardized, language-concordant hospital discharge instructions on postdischarge medication questions. Journal of hospital medicine 2023.
Khoong EC, Sherwin EB, Harrison JD, Wheeler M, Shah SJ, Mourad M, Khanna R.